Human Synovial Digest Medium is a precisely optimized, ready-to-use enzymatic digestion solution specifically designed for the efficient and gentle isolation of highly viable and functionally intact primary cells from human synovial tissue. Its core mechanism employs a synergistic enzyme system comprising collagenase and neutral proteases to rapidly dissociate synovial tissue while maximally preserving cell surface receptors and proliferative potential. This effectively addresses the challenges of low cell yield and compromised viability associated with conventional methods, providing a reliable and consistent source of high-quality primary cells for synovial cell pathomechanism research, drug screening, and target identification in diseases such as rheumatoid arthritis and osteoarthritis.