This product is a serum-free medium for QOR/2E11 cells, a specialized formulation precisely engineered based on the concept of chemically defined (CD) media. It is specifically designed for high-density suspension culture and efficient recombinant protein expression in the North American quail transformed cell line (QOR/2E11). Its core components integrate metabolomics analysis with AI-assisted design to enhance key post-translational modification cofactors, energy metabolism regulators, and cellular stress protection networks. This addresses the cell line's unique high-efficiency folding and secretion capabilities for therapeutic protein and complex biopharmaceutical production. The formulation ensures consistent product quality while significantly boosting yield per unit volume and process robustness.