This product is a specialized medium based on the classic RPMI 1640 formulation, specifically optimized for low-serum culture environments. Through precise addition of specific growth factors, lipids, and serum-free supplements such as insulin-transferrin-selenium (ITS), it significantly reduces fetal bovine serum concentration to 1%-2%. This formulation consistently supports optimal growth of lymphocytes, hybridoma cells, and various tumor cells while minimizing batch-to-batch serum variability that can interfere with experiments. It ensures exceptional stability and reproducibility of culture outcomes.